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X Demographics
Mendeley readers
Attention Score in Context
| Title |
An Expanded View of Complex Traits: From Polygenic to Omnigenic
|
|---|---|
| Published in |
Cell, June 2017
|
| DOI | 10.1016/j.cell.2017.05.038 |
| Pubmed ID | |
| Authors |
Evan A. Boyle, Yang I. Li, Jonathan K. Pritchard |
| Abstract |
A central goal of genetics is to understand the links between genetic variation and disease. Intuitively, one might expect disease-causing variants to cluster into key pathways that drive disease etiology. But for complex traits, association signals tend to be spread across most of the genome-including near many genes without an obvious connection to disease. We propose that gene regulatory networks are sufficiently interconnected such that all genes expressed in disease-relevant cells are liable to affect the functions of core disease-related genes and that most heritability can be explained by effects on genes outside core pathways. We refer to this hypothesis as an "omnigenic" model. |
X Demographics
The data shown below were collected from the profiles of 771 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 250 | 32% |
| United Kingdom | 61 | 8% |
| Canada | 20 | 3% |
| Spain | 18 | 2% |
| Australia | 16 | 2% |
| France | 15 | 2% |
| Germany | 14 | 2% |
| Netherlands | 10 | 1% |
| Italy | 8 | 1% |
| Other | 96 | 12% |
| Unknown | 263 | 34% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 378 | 49% |
| Members of the public | 354 | 46% |
| Practitioners (doctors, other healthcare professionals) | 22 | 3% |
| Science communicators (journalists, bloggers, editors) | 16 | 2% |
| Unknown | 1 | <1% |
Mendeley readers
The data shown below were compiled from readership statistics for 3,319 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 14 | <1% |
| United Kingdom | 4 | <1% |
| Spain | 3 | <1% |
| Italy | 2 | <1% |
| Sweden | 2 | <1% |
| Korea, Republic of | 1 | <1% |
| Switzerland | 1 | <1% |
| Hong Kong | 1 | <1% |
| Norway | 1 | <1% |
| Other | 9 | <1% |
| Unknown | 3281 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 825 | 25% |
| Researcher | 660 | 20% |
| Student > Master | 342 | 10% |
| Student > Bachelor | 299 | 9% |
| Student > Doctoral Student | 158 | 5% |
| Other | 518 | 16% |
| Unknown | 517 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 937 | 28% |
| Biochemistry, Genetics and Molecular Biology | 902 | 27% |
| Medicine and Dentistry | 209 | 6% |
| Neuroscience | 133 | 4% |
| Computer Science | 107 | 3% |
| Other | 378 | 11% |
| Unknown | 653 | 20% |
Attention Score in Context
This research output has an Altmetric Attention Score of 782. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 November 2023.
All research outputs
#23,621
of 24,887,826 outputs
Outputs from Cell
#181
of 17,092 outputs
Outputs of similar age
#439
of 321,812 outputs
Outputs of similar age from Cell
#5
of 135 outputs
Altmetric has tracked 24,887,826 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 17,092 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 58.0. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 321,812 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 135 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 97% of its contemporaries.